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EPILEPSY OF INFANCY WITH MIGRATING FOCAL SEIZURES

GENETICS

PATTERN OF INHERITANCE

No familial inheritance has been reported. De novo gene abnormalities are implicated.

KNOWN GENES

A variety of genetic etiologies have been associated with this syndrome including gene abnormalities in KCNT1, SCN1A, SCN2A, PLCB1, TBC1D24 and CHD2.

FAMILY HISTORY OF SEIZURES/EPILEPSY

It is not typical to have a family history of epilepsy or febrile convulsions, however rare cases are reported where such a family history was present.

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