EPILEPTIC ENCEPHALOPATHY WITH CONTINUOUS SPIKE-AND-WAVE DURING SLEEP

• Lennox Gastaut syndrome - the presence of generalized tonic seizures suggests Lennox Gastaut syndrome, focal motor seizures are rare in Lennox Gastaut syndrome
• Landau-Kleffner syndrome - acquired aphasia is the predominant feature, seizures are uncommon, interictal EEG focality is mainly temporal rather than frontal, continuous spike-and-wave during sleep typically occurs at some time in Landau Kleffner syndrome but is pathognomonic for epileptic encephalopathy with continuous spike-and-wave during sleep.
• Cognitive regression due to other etiologies