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EPILEPTIC ENCEPHALOPATHY WITH CONTINUOUS SPIKE-AND-WAVE DURING SLEEP

  • Lennox Gastaut syndrome - the presence of generalized tonic seizures suggests Lennox Gastaut syndrome, focal motor seizures are rare in Lennox Gastaut syndrome
  • Landau-Kleffner syndrome - acquired aphasia is the predominant feature, seizures are uncommon, interictal EEG focality is mainly temporal rather than frontal, continuous spike-and-wave during sleep typically occurs at some time in Landau Kleffner syndrome but is pathognomonic for epileptic encephalopathy with continuous spike-and-wave during sleep.
  • Cognitive regression due to other etiologies
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