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HIPPOCAMPAL SCLEROSIS

GENETICS

PATTERN OF INHERITANCE

Hippocampal sclerosis is an acquired abnormality.

KNOWN GENES

Not applicable in most cases - hippocampal sclerosis is an acquired abnormality. However, febrile seizures, especially if prolonged, can cause hippocampal sclerosis. Genetic epilepsies that are associated with febrile seizures (such as Dravet syndrome, Febrile Seizures Plus) can therefore predispose an individual to the development of hippocampal sclerosis.

FAMILY HISTORY

This may be present if there is a genetic co-occurring condition associated with prior febrile seizures (see above).

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