ILAE Logo
Epilepsy Diagnosis Logo

EPILEPSY WITH MYOCLONIC-ATONIC SEIZURES

GENETICS

PATTERN OF INHERITANCE

Complex/polygenic inheritance with variable penetrance.

KNOWN GENES

A minority of cases may be explained by variants in SCN1A and SLC2A1.

FAMILY HISTORY OF SEIZURES/EPILEPSY

There is frequently a family history of febrile seizures (in 50% of cases); other seizures/epilepsy syndromes may also occur in families. Epilepsy with myoclonic-atonic seizures is seen in families with other individuals with genetic epilepsy with febrile seizures plus, suggesting common genetic etiological factors.

Feedback | Home | Contact Us | Privacy | Terms & Conditions of Use | Log In For Videos
Creative Commons License
This website is owned by the International League Against Epilepsy. Text on this website, last updated July 15, 2022,
is available under a Creative Commons Attribution-ShareAlike 4.0 International License,
EXCEPTING all videos and images, which remain copyrighted by the International League Against Epilepsy.