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EPILEPSY WITH GENERALIZED TONIC-CLONIC SEIZURES ALONE

GENETICS

PATTERN OF INHERITANCE

Complex/polygenic inheritance.

KNOWN GENES

CLCN2 and others.

FAMILY HISTORY OF SEIZURES/EPILEPSY

A family history of epilepsy is common (in 20%, commonly the same epilepsy syndrome). A family history of febrile seizures is reported in around 10% of cases.

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