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MYOCLONIC ENCEPHALOPATHY IN NON-PROGRESSIVE DISORDERS

Background

The background is typically abnormal with slow (theta-delta) activity seen, predominantly in the central or parieto-occipital regions.

Interictal

The interictal EEG shows multifocal continuous spikes, sharp waves, or continuous slow waves.

Activation

Spikes may be superimposed on parieto-occipital slow activities with eye closure.

EEG abnormality persists in early sleep cycles, but in later sleep cycles in the night and in slow wave sleep, the abnormality improves and myoclonic jerks cease.

Ictal

Myoclonic jerks may not correlate with EEG findings or may be accompanied by diffuse or multifocal slow spike-and-wave discharges or by anterior-predominant rhythmic theta or delta activities.

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